Sunday, June 22, 2008
Pharmacologic Elevation of Blood Pressure for Acute Brain Ischemia
Abstract Introduction Several studies demonstrated that patients with low blood pressure upon presentation with acute ischemic stroke have worse outcomes. Elevated mean arterial pressure (MAP) directly improves cerebral perfusion. Phenylephrine is a selective alpha-1 agonist with peripheral vasoconstrictive effect, raising the blood pressure without constricting brain vessels.
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