Spontaneous breathing during airway pressure release ventilation in experimental lung injury: effects on hepatic blood flow

Abstract Objective  Positive pressure ventilation can affect systemic haemodynamics and regional blood flow distribution with negative effects on hepatic blood flow. We hypothesized that spontaneous breathing (SB) with airway pressure release ventilation (APRV) provides better systemic and hepatic blood flow than APRV without SB.

Relationship between increased blood pressure and hematocrit during modified ultrafiltration for pediatric open heart surgery

Abstract Objective  Modified ultrafiltration increases blood pressure after cardiopulmonary bypass in children. To investigate the cause of this hemodynamic improvement, we assessed the relationship between increased blood pressure and hematocrit.

Variation in Blood Pressure as a Guide to Volume Loading in Children Following Cardiopulmonary Bypass

Abstract Objective  Intravascular volume loading is used to optimize cardiac output in children following weaning from cardiopulmonary bypass. Central venous pressure (CVP) is frequently used to titrate fluid administration but it is often misleading in predicting fluid responsiveness. Variation in the arterial pressure waveform is exaggerated in patients with deficient intravascular volume and has been shown to be a good predictor of fluid responsiveness in adults following cardiac surgery. The aim of this study was to compare the measures of variation in blood pressure as a guide to volume loading in children following cardiopulmonary bypass.

Total antioxidant status and 8-hydroxy-2’-deoxyguanosine levels in gingival and peripheral blood of periodontitis patients

Abstract Introduction:  The aim of this study was to determine 8-OHdG concentration as a biomarker of oxidant-induced DNA damage and to assess total antioxidant status (TAS) in gingival and peripheral blood during periodontal lesion.

Regional cerebral blood flow abnormalities in patients with primary hyperparathyroidism

Abstract Introduction  We assessed the alterations in regional cerebral blood flow (rCBF) in patients with primary hyperparathyroidism (PHP) before parathyroidectomy by semiquantitative analysis of brain single photon emission computed tomography (SPECT) images.

A new tourniquet system that determines pressures in synchrony with systolic blood pressure

Abstract Introduction  This study reports the results of the clinical use of a new tourniquet system for surgery of the lower extremity that can determine tourniquet pressure in synchrony with systolic blood pressure.

Pharmacologic Elevation of Blood Pressure for Acute Brain Ischemia

Abstract Introduction  Several studies demonstrated that patients with low blood pressure upon presentation with acute ischemic stroke have worse outcomes. Elevated mean arterial pressure (MAP) directly improves cerebral perfusion. Phenylephrine is a selective alpha-1 agonist with peripheral vasoconstrictive effect, raising the blood pressure without constricting brain vessels.